Ingredient record · Enzyme combination sold to reduce swelling
Trypsin-chymotrypsin: bans, restrictions and failed batches in India
Last checked 20 September 2026. Sources: CDSCO banned-drugs notifications and monthly NSQ alerts, Jan 2019 to Jul 2026
2 entries containing Trypsin-chymotrypsin are on India's banned-drugs list, and 1 is banned today. 22 batches of medicines containing Trypsin-chymotrypsin failed a government lab test between November 2019 and June 2026, from 15 manufacturers. A failed batch concerns that batch only, not the medicine or every brand.
1
Banned combinations in force
1
Other listed orders (stayed, restricted, quashed)
22
Batches failed a lab test
Jun 2026
Latest lab alert
Is it banned? Our answer pages
Not banned · spurious batches reported
On the banned-drugs list
Trypsin-chymotrypsin on its own is not on CDSCO's banned list. The entries below are specific combinations that contain it. Status follows CDSCO's own notes on each entry.
| Drug / combination | Action | Notification | Date | Order | Status note |
|---|---|---|---|---|---|
| Lornoxicam + Paracetamol + TrypsinFixed-dose combination · gi | Banned | S.O. 4400(E) | 7 September 2018 | 328 FDCs · Sep 2018 | In force per CDSCO list as on 22.11.2021 |
| Lornoxicam + Paracetamol + TrypsinFixed-dose combination · gi | Quashed | S.O. 728(E) | 10 March 2016 | 344 FDCs · Mar 2016 | Quashed by Delhi HC 1 Dec 2016; see 2018 re-ban |
Products that failed lab tests
Product names as printed by the testing labs, grouped. Open a product to see every batch number.
| Product | Batches | Makers | Latest |
|---|---|---|---|
| Trypsin Chymotrypsin | 7 | 7 | Jun 2026 |
| Trypsin Bromelain Rutoside Trihydrate | 6 | 3 | Jan 2024 |
| Trypsin Chymortypsin | 1 | 1 | Nov 2025 |
| Trypsin Let Chymotryp | 1 | 1 | Jul 2025 |
| Trypsin Bromelain Rutoside Trihydrate Diclofenac | 1 | 1 | May 2025 |
| Kivoral Forte | 1 | 1 | Apr 2025 |
| Trypsin Bromelain Rutoside Trihydrate Flavoshine | 1 | 1 | Sep 2024 |
| Chymovit Forte | 1 | 1 | Jul 2023 |
| Chymnetra Forte | 1 | 1 | Jan 2023 |
| Chymocip | 1 | 1 | Mar 2021 |
| Tymolytic Ap | 1 | 1 | Feb 2020 |
Most recent failed batches
| Product | Batch | Manufacturer | Reason declared NSQ | Tested by | Alert |
|---|---|---|---|---|---|
| Trypsin-Chymotrypsin Tablets | 2KU6M021Mfg 2025-05 · Exp 2028-04 | Torrent Pharmaceuticals LtdSikkim | The sample does not conform to Manufacturer's specification with respect to Assay of Trypsin-Chymotrypsin activity.Assay | CDL KolkataCDSCO lab | Jun 2026 |
| Trypsin-Chymortypsin Tablets | 2KU6L012Mfg 2024-02 · Exp 2027-01 | Torrent Pharmaceuticals LtdSikkim | Enzymatic Activity (Trypsin & Chymotrypsin) and Disintegration (Acid stage)Disintegration | Food & Drugs Laboratory, VadodaraState lab | Nov 2025 |
| Trypsin-Chymotrypsin Tablets (CHYMORAL FORTE DS) | WBB1E020Mfg 2024-12 · Exp 2026-11 | Windlas Biotech Limited (Plant-2)Uttarakhand | The sample is not of standard quality for the reason stated under 'Description'.Description | CDL, KolkataCDSCO lab | Oct 2025 |
| Trypsin & let Chymotryp | G240147/2Mfg 2024-09 · Exp 2026-08 | Vee Excel Drugs & Pharmaceuticals (P) LtdUttar Pradesh | The sample failed in Assay (Label claim 13.6%) for Trypsin-Chymotrypsin.Assay | DCA Vijayawada, Andhara PradeshState lab | Jul 2025 |
| Trypsin, Bromelain, Rutoside, Trihydrate & Diclofenac Tablets (RUMIHEAL-D) | SRTF240703BMfg 2024-06 · Exp ? | Systole Remedies Pvt. LtdHimachal Pradesh | Test for DisintegrationDisintegration | DTL Baddi Distt Solan HPState lab | May 2025 |
| Kivoral Forte(Trypsin and Chymotrypsin Tablets) | SB-4242Mfg 2023-07 · Exp 2025-06 | Sano-Cito Thereapeutics IncHimachal Pradesh | The enzymatic activity of trypsin chymotrypsin in the sample is less (i.e. 40.52%) of the labelled amount) than the permissible limits.Labelling | CDTL MumbaiCDSCO lab | Apr 2025 |
| Trypsin & Chymotrypsin Tablets (Lysoflam Forte) | LFTF24002CMfg 2024-06 · Exp 2026-05 | Cachet Pharmaceuticals Pvt. LtdHimachal Pradesh | Assay of Trypsin & ChymotrypsinAssay | CDL KolkataCDSCO lab | Oct 2024 |
| Trypsin, Bromelain & Rutoside Trihydrate Tablets [Flavoshine] | TTF24065Mfg 2024-06 · Exp 2025-11 | Tiruvision MedcareHimachal Pradesh | The sample fails the test ?Disintegration? specified in the Laboratory protocol as per IPDisintegration | DTL ThiruvananthapuramState lab | Sep 2024 |
| Trypsin, Bromelain & Rutoside Trihydrate Tablets | PF8CC12Mfg 2023-08 · Exp 2025-07 | Pure & Cure Healthcare Pvt. LtdUttarakhand | Assay of 'Trypsin'Assay | CDL KolkataCDSCO lab | Jan 2024 |
| Trypsin, Bromelain & Rutoside Trihydrate Tablets (Rednil) | DMT1197BMfg 2023-08 · Exp 2025-07 | Dm Pharma Private LimitedHimachal Pradesh | Assay/content of 'Trypsin'Assay | CDL KolkataCDSCO lab | Dec 2023 |
| Trypsin-Chymotrypsin Tablets (Chymnetra-Forte) | DT1624HMfg 2022-12 · Exp 2024-11 | Dm Pharma Private LimitedHimachal Pradesh | Uniformity of Weight, & Average WeightUniformity of weight/content | CDTL MumbaiCDSCO lab | Jul 2023 |
| Chymovit Forte (Trypsin- Chymotrypsin Tablets) | DMT0027 JMfg 2023-01 · Exp 2024-12 | Dm Pharma Private LimitedHimachal Pradesh | Uniformity of Weight, Average Weight & Disintegration test (Acid stage)Disintegration | CDTL MumbaiCDSCO lab | Jul 2023 |
| Trypsin- Chymotrypsin Tablets (CHYMORAL FORTE TABLETS) | 2JH3H019Mfg 2021-04 · Exp 2023-03 | Nestor Pharmaceuticals LimitedHaryana | Disintegration test (Acid Medium)Disintegration | RDTL ChandigarhState lab | Jan 2023 |
| Chymnetra-Forte (Trypsin- Chymotrypsin Tablets) | TTP-22017Mfg 2022-02 · Exp 2025-01 | Torrent Pharmaceuticals LtdSikkim | Disintegration time and AssayAssay | CDTL MumbaiCDSCO lab | Jan 2023 |
| Trypsin, Bromelain & Rutoside Trihydrate Tablets | GT201572Mfg 2020-11 · Exp 2022-10 | Theon Pharmaceuticals LtdHimachal Pradesh | Description Length Thickness and WidthDescription | CDTL MumbaiCDSCO lab | Mar 2022 |
Showing 15 of 22 records
Holding a strip or bottle? The batch number is printed after "B. No." Check it against every alert. If it matches, return it to the pharmacy. What the labels mean: status guide.